The Management Committee (MC) consists of the National Node Directors of all member states of BBMRI-ERIC. Observer countries may be invited to participate. The MC is chaired by the Director General. It may elect a Vice Chair for the duration of one calendar year and may be re-elected on not more than two consecutive occasions.

The MC contributes to and supports the Director General in the development of a draft annual Work Programme and a draft budget together with a preliminary draft Work Programme and a draft budget for the following two years. The MC also supports the Director General in the execution of the Work Programme and is responsible for enabling efficient interaction between BBMRI-ERIC and the Partner Biobanks of Members.